Do you think maybe Callie is sad because she thinks Arizona is sad? Do you think she can sense that Arizona is not completely happy and that’s why she has that look on her face? She thinks a new baby will make her happy because she knows how much Sofia makes Arizona happy. If you re watch 11x01, a smile that truly reaches Callie’s eyes comes when Arizona is talking about the surgery with Doctor Herman? Arizona eyes lit up when she talked about the amazing thing that Dr. Geena did. Look at Callie at that moment, a smile reaches her eyes when she thinks Arizona is truly glowing and happy.